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Gadolinium-DTPA-Enhanced Magnetic Resonance Imaging in Intractable Partial Epilepsy Neurol 39:1115-1118, Cascino,G.D.,et al, 1989 See this aricle in Pubmed Article Abstract We performed magnetic resonance imaging(MRI),before and after the administration of gadolinium-DTPA(Gd-DTPA),in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder.In most patients,61%,unenhanced and enhanced MRI studies were negative.In 26%the unenhanced image was positive,and the abnormality enhanced with Gd-DTPA.In 13%the unenhanced MR image was positive,but the abnormality did not enhance with Gd-DTPA.Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.

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